The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
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Osteoid osteoma of the foot and ankle can be challenging to diagnose. A case of an osteoid osteoma of the posterior talar dome is presented in this article. The lesion mimicked other local pathologies resulting in considerable delay in diagnosis and unnecessary therapeutic interventions. Osteoid osteoma should be included in the differential diagnosis of intractable hindfoot pain.
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Does a single application of PRP alter the expression of IGF-I in the early phase of tendon healing?
The purpose of this study was to determine whether or not a single application of platelet-rich plasma (PRP) in a ruptured tendon alters the expression of IGF-I in the early phase of healing in an animal wound model. We performed an Achilles tendon rupture model on 48 New Zealand white rabbits, by transecting the tendon transversely and then injecting 0.5 mL of PRP into the tendon mass on one side, and injecting saline on the contralateral, control side. Twenty-four animals received PRP (PRP group), and 24 animals served as untreated controls (control group). ⋯ The growth factor was localized in the epitenon and the endotenon, with an overexpression in the epitenon in the PRP group by the fourth week in comparison with the controls. Furthermore, the tendons treated with PRP healed more rapidly. Based on these findings, PRP could be useful to surgeons treating ruptured tendon.