Anaesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Oral lormetazepam in premedication. A comparison with diazepam.
Lormetazepam, a relatively new benzodiazepine was compared in a randomised, double blind trial with diazepam for its effectiveness as an oral premedicant drug. A scoring system was used to assess sedation, relief of anxiety, nausea, dizziness and cardiovascular effects in two groups of patients having orthopaedic operations. Some statistical indication that lormetazepam has a greater anxiolytic effect than diazepam was found, but in assessing total effect using a known scoring system, no difference was demonstrated between the two drugs.
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Case Reports
Epidural anaesthesia in von Hippel-Lindau disease. Management of childbirth and anaesthesia for caesarean section.
The management of childbirth, including epidural anaesthesia for Caesarean section is described in a patient with von Hippel-Lindau disease. The reasons for the choice of epidural anaesthesia are explained and the anaesthetic significance of the disease is discussed.
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A case of accidental subdural catheterisation is presented, and its course is compared with previously reported subdural injections of local anaesthetic agents. The importance of obtaining proof of the site of malposition of an epidural catheter is stressed.
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A short description of the life of Nikolai Ivanovich Pirogoff and some of his accomplishments are given. His book on administration of ether for anaesthesia (analgesia) by inhalation and by rectum is of special interest. ⋯ Later he tended to favour chloroform, which he considered to be better. He accomplished a lot in life and was highly regarded at home and abroad.