Anaesthesia
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Randomized Controlled Trial Comparative Study Clinical Trial
Lignocaine 2% with adrenaline for epidural caesarean section. A comparison with 0.5% bupivacaine.
A randomised double blind controlled trial of freshly prepared 2% lignocaine with 1/200,000 adrenaline and 0.5% plain bupivacaine was conducted on 60 women undergoing elective Caesarean section. The use of the former enabled epidural blockade to above the T6 dermatome to be established in a significantly shorter time than with bupivacaine (p less than 0.005). The quality of sensory blockade and incidence of complications was similar in the two groups. ⋯ Motor blockade was more intense with 2% lignocaine with adrenaline (p less than 0.03). More neonates had moderately depressed Apgar scores (5-7) at one minute in the lignocaine group but this difference was not statistically significant, and there was no difference in the distribution of Apgar scores at 3 minutes. Lignocaine with 1/200,000 adrenaline is a useful alternative to 0.5% plain bupivacaine when it is desired to establish rapidly epidural blockade for Caesarean section.