Anaesthesia
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The new Score for Prediction Of Postoperative Respiratory Complications (SPORC-2) more reliably predicts the need for early post-operative re-intubation.
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Multicenter Study
A survey of antenatal and peripartum provision of information on analgesia and anaesthesia.
Why is this relevant?
Anaesthetists and anesthesiologists have long worried about the recall of labouring women when presented with risk-benefit discussions prior to epidural analgesia or receiving anaesthesia for cesarean section.
This UK survey of over 900 women across 28 Greater London hospitals explored recall of this antenatal and intrapartum information, along with maternal satisfaction.
What did they find?
There was very little recall of receiving either thorough labour analgesia information (9%) or anaesthesia for CS (12%) provided during the antenatal period.
During the interpartum period, fewer than two-thirds (62%) recalled receiving thorough information during labour before insertion, and less than one-third (28%) before Caesarean section anaesthesia.
13% of women did not recall receiving any information before epidural insertion.
These are concerning findings in a modern era where patient autonomy and informed consent are prioritised, and more so where informed decision making may contribute to a positive birth experience.
Interestingly, verbal information appeared best recalled (OR 5.9 to 20.7 across different categories), although this is counter to past studies showing superiority of written information.
Be clear
Because the 28 hospitals contributing to the survey had large practice differences in how antenatal anaesthetic information was provided, it is difficult to determine whether the provision of information or recall itself is the problem.
Take-home...
Regardless of the cause, a large proportion of pregnant women did not recall being adequately informed before epidural analgesia or caesarean anaesthesia. This needs to be improved.
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Unplanned intensive care admission is a devastating complication of lung resection and is associated with significantly increased mortality. We carried out a two-year retrospective national multicentre cohort study to investigate the influence of anaesthetic and analgesic technique on the need for unplanned postoperative intensive care admission. All patients undergoing lung resection surgery in 16 thoracic surgical centres in the UK in the calendar years 2013 and 2014 were included. ⋯ Patients receiving total intravenous anaesthesia (OR 0.50 (95%CI 0.34-0.70)), and patients receiving epidural analgesia (OR 0.56 (95%CI 0.41-0.78)) were less likely to have an unplanned admission to intensive care after thoracic surgery. This large retrospective study suggests a significant effect of both anaesthetic and analgesic technique on outcome in patients undergoing lung resection. We must emphasise that the observed association does not directly imply causation, and suggest that well-conducted, large-scale randomised controlled trials are required to address these fundamental questions.
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Multicenter Study
The association between platelet dysfunction and adverse outcomes in cardiac surgical patients.
Haemostatic activation during cardiopulmonary bypass is associated with prothrombotic complications. Although it is not possible to detect and quantify haemostatic activation directly, platelet dysfunction, as measured with point-of-care-assays, may be a useful surrogate. In this study, we assessed the association between cardiopulmonary bypass-associated platelet dysfunction and adverse outcomes in 3010 cardiac surgical patients. ⋯ The median (IQR [range]) percentage platelet dysfunction was less for those without the outcome as compared with those with the outcome; 14% (8-28% [1-99%]) vs. 19% (11-45% [2-98%]), p < 0.001. After risk adjustment, platelet dysfunction was independently associated with the composite outcome (p < 0.001), such that for each 1% increase in platelet dysfunction there was an approximately 1% increase in the composite outcome (OR 1.012; 95%CI 1.006-1.018). This exploratory study suggests that cardiopulmonary bypass-associated platelet dysfunction has prognostic value and may be a useful clinical measure of haemostatic activation in cardiac surgery.