The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
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Am J Geriatr Psychiatry · Oct 2009
Meta AnalysisThe association between delirium and the apolipoprotein E epsilon 4 allele: new study results and a meta-analysis.
To determine a possible association between Apolipoprotein E (APOE)sigma4-allele and delirium in a large cohort and combining these current data with former studies in a meta-analysis. ⋯ This study and meta-analysis suggest an association between delirium and the APOE sigma4 allele.
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Am J Geriatr Psychiatry · Oct 2009
Self-reported pain in persons with dementia predicts subsequent decreased psychosocial functioning.
Pain self-report is the assessment gold standard in cognitively intact populations but has been discouraged in persons with dementia because of significant evidence that pain intensity is often underreported by persons with dementia. However, most community-dwelling persons with dementia are cared for in primary care settings where a more in depth pain assessment is unlikely. Therefore, it is vital to know the clinical predictive value of self-report pain assessment in this population. Psychosocial functioning is a meaningful focus for clinical prediction, because psychosocial constructs are integrally related to quality of life, physical functioning, and one's ability to function in the presence of pain. The purpose of this study was to investigate the degree to which answers to simple self-report pain questions can predict changes in psychosocial functioning 4 months later in community-dwelling older adults with dementia. ⋯ Our results suggest that persons with dementia who affirmatively respond to pain questions are at higher risk for developing negative psychosocial states.