The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
-
Am J Geriatr Psychiatry · Apr 2010
Randomized Controlled TrialSertraline for the treatment of depression in Alzheimer disease: week-24 outcomes.
Depression and antidepressant use are common in Alzheimer disease (AD), but the effect of antidepressant treatment for depression on longer term outcomes is unknown. The authors report the Week-24 outcomes of patients who participated in a 12-week efficacy study of sertraline for depression of AD. ⋯ Sertraline treatment is not associated with delayed improvement between 12 and 24 weeks of treatment and may not be indicated for the treatment of depression of AD.