The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
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Am J Geriatr Psychiatry · Jan 2014
Randomized Controlled Trial Multicenter StudyAcute and long-term treatment of late-life major depressive disorder: duloxetine versus placebo.
To compare the efficacy of duloxetine with placebo on depression in elderly patients with major depressive disorder. ⋯ Although the antidepressant efficacy of duloxetine was not confirmed by the primary outcome, several secondary measures at multiple time points suggested efficacy. Duloxetine had significant and meaningful beneficial effects on pain.