Ocular immunology and inflammation
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Ocul. Immunol. Inflamm. · Dec 2012
ReviewAncillary testing, diagnostic/classification criteria and severity grading in Behçet disease.
Since there is no pathognomonic clinical sign or laboratory test to distinguish Behçet disease from other uveitic entities, the diagnosis must be made based on characteristic ocular and systemic findings in the absence of evidence of other disease that can explain the findings. Ancillary tests, including ocular and brain imaging studies, are used to assess the severity of intraocular inflammation and systemic manifestations of Behçet disease, to identify latent infections and other medical conditions that might worsen with systemic treatment, and to monitor for adverse effects of drugs used. There are two diagnostic or classification criteria in general use by the uveitis community, one from Japan and one from an international group; both rely on a minimum number and/or combination of clinical findings to identify Behçet disease. Finally, several grading schemes have been proposed to assess severity of ocular disease and response to treatment.
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To compare the evidence base and systemic treatment strategies for sarcoidosis. ⋯ Limited high-quality evidence exists for the systemic treatment of sarcoidosis, in particular intraocular disease.
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Ocul. Immunol. Inflamm. · Apr 2011
Case ReportsFrosted branch angiitis, presumably related to dermatomyositis.
To report the first case of frosted branch angiitis associated with dermatomyositis in a Korean woman. ⋯ To the best of the authors' knowledge, this is the first case of frosted branch angiitis associated with dermatomyositis. Dermatomyositis should be considered in the differential diagnosis of patients presenting with frosted branch angiitis.
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To report a case of toxic anterior uveitis probably secondary to the use of topical podophyllum. ⋯ Anterior uveitis may occur after topical application of podophyllum.