Der Anaesthesist
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Randomized Controlled Trial Comparative Study Clinical Trial Controlled Clinical Trial
A comparison of alfentanil and fentanyl in short operations with special reference to their duration of action and postoperative respiratory depression.
Ninety women undergoing short gynaecological operations were included in a double-blind comparison of fentanyl and alfentanil, a structurally related and very short-acting narcotic analgesic. Anaesthesia was induced by methohexitone followed by a double-blind injection of either alfentanil (0.5 mg/ml) or fentanyl (0.05 mg/ml). ⋯ Cardiovascular parameters remained stable with both analgesics. There were no troublesome side-effects.