Der Anaesthesist
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Randomized Controlled Trial Comparative Study Clinical Trial Controlled Clinical Trial
[Prevention of myocardial ischemia. Study following aortocoronary bypass operation with the calcium antagonist diltiazem].
The incidence of postoperative myocardial infarction (MI) is proportional to the incidence of myocardial ischaemic episodes. Therefore, the prevention of such episodes is of great clinical importance. METHODS. ⋯ DIL results in marked haemodynamic stabilisation during CABG, especially in the period immediately after extra-corporeal circulation. This might serve as an explanation for the significant reduction in ischaemic episodes in the DIL group compared to the other two groups. Therefore, perioperative prevention of myocardial ischaemia with the calcium antagonist DIL seems to be favourable in patients during CABG.