Journal of chromatography. A
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Matrix solid-phase dispersion (MSPD) and gas chromatography-mass spectrometry were used for the rapid determination of 18 plasticizers (phthalates and adipates), 7 polycyclic musks and 5 nitromusks, which makes a total of 30 targets, in both rinse-off and leave-on cosmetic formulations. The MSPD method was miniaturized and customized to avoid or minimize risks of phthalate contamination and to reduce residues and costs. The amount of sample and extraction solvent employed were 0.1g and 1mL, respectively. ⋯ Twenty-five out of thirty targets were detected in the samples. The most frequently found compounds were galaxolide and tonalide reaching concentrations above 0.1% (1000μgg(-1)), and diethyl phthalate (between 0.7 and 357μgg(-1)). The presence of banned substances (Regulation (EC) No. 1223/2009) such as dibutyl phthalate, diisobutyl phthalate, dimethoxyethyl phthalate, benzylbutyl phthalate, diethylhexyl phthalate, diisopentyl phthalate and dipentyl phthalate, musk ambrette and musk tibetene was confirmed in sixteen of the twenty-six personal care products (62%).