Current opinion in neurology
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This review discusses the advances in the treatment of status epilepticus since the first London-Innsbruck Colloquium on Status Epilepticus, held in London in April 2007. ⋯ There have been a number of advances in recent years in the treatment of status epilepticus. In stage 2 and stage 3 of status epilepticus, the therapies have almost invariably been assessed in open studies only, and there is a need for multicentre randomized controlled therapy comparisons.
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There is a complex relationship between epilepsy, sleep and sleep disorders. Recent studies have provided new insights into the links between the disorders that may facilitate differential diagnosis and treatment but may also improve our understanding of underlying pathophysiological mechanisms. ⋯ Accurate identification and diagnosis of sleep disorders as well as epilepsy is clinically important to ensure optimal treatment of both epilepsy and sleep disorders. Further studies of these nocturnal events may advance our understanding of underlying pathological mechanisms and the complex relationship between sleep and epilepsy.