Current opinion in neurology
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Curr. Opin. Neurol. · Oct 2014
ReviewClinical and scientific aspects of muscle-specific tyrosine kinase-related myasthenia gravis.
Antibodies to muscle-specific tyrosine kinase (MuSK) characterize up to 5% of myasthenia gravis patients. This review focuses on the differences to clinical antiacetylcholine receptor-myasthenia gravis, and on the physiology and animal studies that elucidate the role of MuSK and help explain the clinical disease. ⋯ MuSK myasthenia gravis has distinct clinical and pathophysiological features.