American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Feb 2014
Spirometry and Health Status Worsen with Weight Gain in Obese but Improve in Normal-weight Smokers.
The literature on the effect of obesity and weight gain on respiratory outcomes in smokers is contradictory. ⋯ Weight gain affects respiratory outcomes differently between obese and normal-weight smokers. Whereas FEV1 and health status decrease with weight gain among obese smokers, they improve among normal-weight smokers. The nonlinear relationship between weight gain and respiratory outcomes suggests that this effect of excess weight is unlikely to be mechanical alone.