American journal of respiratory and critical care medicine
-
Am. J. Respir. Crit. Care Med. · Jun 2015
Randomized Controlled Trial Multicenter StudyBudesonide/Formoterol for Bronchiolitis Obliterans After Hematopoietic Stem Cell Transplantation.
Systemic steroids are the standard treatment for bronchiolitis obliterans syndrome (BOS) after allogeneic hematopoietic stem cell transplantation (HSCT) despite their poor efficacy and disabling side effects. ⋯ Budesonide/formoterol administration led to a significant improvement in the FEV1 in patients with mild/severe BOS after allogeneic HSCT. Clinical trial registered with www.clinicaltrials.gov (NCT00624754).