American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Feb 2016
Retraction Of PublicationRetraction: Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1; Heightened Endoplasmic Reticulum Stress in the Lungs of Patients with Chronic Obstructive Pulmonary Disease: The Role of Nrf2-Regulated Proteasomal Activity.
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Am. J. Respir. Crit. Care Med. · Feb 2016
Randomized Controlled Trial Comparative StudyThe Effects of Alternative Resuscitation Strategies on Acute Kidney Injury in Patients with Septic Shock.
Septic shock is a common cause of acute kidney injury (AKI), and fluid resuscitation is a major part of therapy. ⋯ In patients with septic shock, AKI is common and associated with adverse outcomes, but it is not influenced by protocolized resuscitation compared with usual care.
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Am. J. Respir. Crit. Care Med. · Feb 2016
Randomized Controlled TrialRandomized Trial of Apneic Oxygenation during Endotracheal Intubation of the Critically Ill.
Hypoxemia is common during endotracheal intubation of critically ill patients and may predispose to cardiac arrest and death. Administration of supplemental oxygen during laryngoscopy (apneic oxygenation) may prevent hypoxemia. ⋯ Apneic oxygenation does not seem to increase lowest arterial oxygen saturation during endotracheal intubation of critically ill patients compared with usual care. These findings do not support routine use of apneic oxygenation during endotracheal intubation of critically ill adults. Clinical trial registered with www.clinicaltrials.gov (NCT 02051816).