American journal of respiratory and critical care medicine
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Am. J. Respir. Crit. Care Med. · Oct 2018
Multicenter Study Observational StudyValidation of a Host Response Assay, SeptiCyte LAB, for Discriminating Sepsis from Systemic Inflammatory Response Syndrome in the ICU.
A molecular test to distinguish between sepsis and systemic inflammation of noninfectious etiology could potentially have clinical utility. ⋯ SeptiCyte LAB appears to be a promising diagnostic tool to complement physician assessment of infection likelihood in critically ill adult patients with systemic inflammation. Clinical trial registered with www.clinicaltrials.gov (NCT01905033 and NCT02127502).