Croatian medical journal
-
Croatian medical journal · Oct 2021
Case ReportsNecrotic ulcerative stomatitis in a patient with long-standing celiac disease: a case report.
Celiac disease is the most common chronic gastroenterological disease. One of the extraintestinal manifestations of this multifaceted disease are changes in the oral mucosa. However, ulceration leading to the destruction of the soft and hard tissues of the orofacial region has not been reported so far. ⋯ The resulting defect required plastic reconstructive surgery. We successfully compensated for the defect by applying a combination of two flaps from the remaining tissue of the lower lip. Oral competence was established immediately after the operation, and a very good esthetic appearance two months later.
-
Croatian medical journal · Oct 2021
Case ReportsMultifocal micronodular pneumocyte hyperplasia with a novel mutation in TSC1: a case report.
We report on a 34-year-old woman diagnosed with tuberous sclerosis complex. The patient was admitted for respiratory manifestations, while multi-organ involvement made the diagnostic process challenging. ⋯ His699Ter), which expands the disease-causing variant spectrum. Our results may facilitate the disease diagnostics and help to devise genetic counseling and targeted gene therapy.