Medicina
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To examine the incidence of stroke during the first three years after a first-ever myocardial infarction. ⋯ The risk of stroke is identified as the highest one early after the myocardial infarction.
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The objective of our paper was to show the data of our treated patients with malignant pleural mesothelioma. In the Department of Thoracic Surgery of Oncology Institute at Vilnius University from 1980 till 01.06.2002, 33 patients (pts), to whom diagnosis of pleural mesothelioma was confirmed by pathologist, were treated in the Clinic. A malignant pleural mesothelioma was diagnosed in 31 pts, two pts had a non-malignant form of mesothelioma. Among patients were 19 men and 14 women. The distribution of pts according to the stage of the disease was: I stage - 3, II - 1, III - 17, IV - 10. Videothoracoscopy is the best method for diagnosing pleural mesothelioma. Radical operations were performed only in 17 cases: 6 - pulmonectomy with pleuroectomy, 1 - lobectomy, 3 - atypical segmentectomy, 4 - pleuroectomy, 4 - tumorectomy. Thoracotomy was performed in 9 cases. Insufflation of talc was performed in 6 pts. Adjuvant therapy (chemotherapy or radiotherapy) was given to 10 pts. ⋯ 1. Diagnosis of malignant pleural mesothelioma is difficult and confirmation of the disease is possible only after histological examination of tumor. 2. The best results of treatment were achieved after combined treatment: surgery, after chemotherapy and radiotherapy. 3. In cases of pleural effusion of diffuse pleural mesothelioma insufflation of talc or other chemical substances into pleural cavity is recommended.
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Review Comparative Study
[Rehabilitation possibilities of the post-resection defects of facial bones and surrounding soft tissues in cancer patients (review of the literature)].
The review of the scientific literature, concerning contemporary treatment methods and materials of the post-resection defects of facial bones and surrounding soft tissues in cancer patients is presented in this article. The aloplastic endoprostheses, removable post-resection intraoral prostheses, fixed on implants and ectoprostheses, which are reconstructing the defects of soft facial tissues, are analysed more broadly. The advantages and leaks of these treatment methods are discussed, taking into account the problems, which are faced by the patients after the surgical and radiological treatment of malignant tumours of face and jaws. According to the data of Institute of Oncology, Vilnius University and Kaunas Medical University Clinics, from the beginning of the 1999 till the end of the 2000, 63 patients needed the rehabilitation after the treatment of the malignant tumours of face and jaws.
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Review Comparative Study
[Present-day approach to pharmacological and clinical aspects of novel antidepressants].
Depression is the most common illness that affects a large number of individuals in all countries. Recent evidence suggest that depressive episodes if left untreated may heighten severity of subsequent episodes and may increase need for more health care resources. The first antidepressants, tricyclics and monoamine oxidase inhibitors, became available in the late 1950s. ⋯ The combination of antidepressants is an important clinical issue. There are the following principles of combining antidepressants: 1. to combine mechanisms of action not just drugs, 2. to combine antidepressants and to promote pharmacological synergy and tolerability, 3. to use important synergies within the serotonin, noradrenaline and even dopamine monoaminergic systems. Adequate treatment of depression including modern treatment approaches has the potential to reduce suffering and disability substantially and minimise the risk of suicide.
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Comparative Study
[Survival after myocardial infarction among the middle-aged Kaunas men and women].
The aim of the present study was to determine and compare the short-term and long-term survival after myocardial infarction (MI) in the Kaunas men and women aged 25-64 during 1983 to 1998, according to ischemic heart disease register data. The source of the data--Kaunas population-based ischemic heart disease register. The diagnosis of MI was based on the criteria defined by the WHO MONICA Project. All myocardial infarction events that occurred among Kaunas population aged 25-64 years during 1983-1998 were recorded. Myocardial infarction survival was evaluated using Kaplan-Meier method and using z test for comparing the survival curves. ⋯ The data of 3,613 persons with a first myocardial infarction and 528 with a recurrent myocardial infarction were analyzed. Detected, that among men and women a short-term (28 days) survival probability was significant different. In the men aged 25-64 short-term survival after a first myocardial infarction was better comparing with the women survival (z = 4.63, p = 0.03). The short-term survival among men aged 25-64 with a recurrent myocardial infarction comparing with woman did not differ. The long-term survival probability in patients, who survived the first 28 days, among men and women with a first and recurrent myocardial infarction aged 25-64 was without statistically significant differences.