Medicina
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Comparative Study
[Application of methods for hemodynamic monitoring in critical cardiac pathology (an experimental model for assessment of hemodynamics)].
Hemodynamic assessment of critically compromised patients with cardiac pathology is one of the goals of recent diagnostics and treatment strategies. Different methods for assessment of hemodynamics are applied in clinical practice. However, applied methods (invasive and noninvasive) have specific advantages and disadvantages. ⋯ It were selected 6 laboratory animals of different weight and sex. 7 measurements of hemodynamics were performed. Standard methodics was successfully applied in the experimental model. Results, method limitations and recommendations for further studies are presented in the article.
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Comparative Study
[Analysis of burns' causes of children admitted to the National Burns Center in 1995-2000].
A retrospective multifactorial epidemiological study of pediatric patients admitted to the National Burns Center was undertaken, since January 1995 to December 2000. Nine hundred sixty-nine patients were admitted. The objective of this study was to describe the burns characteristics of different pediatric age groups. ⋯ The home was the most common site of injury - 93.4%. The mean patient age was 3.43+/-0.12 (range from 6 months to 16 years). The mean percentage body surface area burned was 8.87+/-0.28 percent.
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Review Comparative Study
[Some aspects of diagnosis and treatment of cervical intraepithelial neoplasia (review of the literature)].
Cervical cancer has remained close to the forefront of oncologic studies even in our days. The incidence of the disease has changed little, except in those countries with effective screening programs. The morbidity in Lithuania reached 23.9/100,000 in the 2000's, while in comparison the morbidity in the 1994's was 20.4/100,000. ⋯ Since 1978 it is known that Human Papillomavirus is closely related to genital neoplasia--cervical, vulva, vagina, penis, anus intraepithelial neoplasia and invasive carcinoma. It is also known that cytologic smear is one of the most important way to diagnose cervical intraepithelial neoplasia and cancer as well, because we can not evaluate cervical lesion visually. Cytologic smear remains the main principle of cancer screening because of its simplicity and accessibility, while colposcopy remains the method of examination in choice, when pathologic cytologic findings are determined.
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Comparative Study
[Myocardial infarct morbidity and mortality trends in the Kaunas population 25-64 years of age during 1983-1998].
The aim of the present study was to evaluate the trends in attack rate, incidence, recurrence and 28-day case-fatality of myocardial infarction (MI) in Kaunas population aged 25-64 during 1983-1998, according to ischemic heart disease register data. The source of data--Kaunas population-based ischemic heart disease register. Trends were analyzed using method of linear regression on logarithms of the age-standardized annual morbidity and lethality rates. ⋯ Among Kaunas women, both attack rates of MI and recurrence rates of MI were increasing statistically significantly, although MI incidence rates remained stable during 1983-1998. The MI 28-day case-fatality rates tended to decrease among both men and women. Further efforts of the primary prevention of the ischemic heart disease are required in order to achieve stable decreasing trends in both attack rate and incidence of MI in the middle-aged Kaunas population.
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Review Comparative Study
[Present-day approach to pharmacological and clinical aspects of novel antidepressants].
Depression is the most common illness that affects a large number of individuals in all countries. Recent evidence suggest that depressive episodes if left untreated may heighten severity of subsequent episodes and may increase need for more health care resources. The first antidepressants, tricyclics and monoamine oxidase inhibitors, became available in the late 1950s. ⋯ The combination of antidepressants is an important clinical issue. There are the following principles of combining antidepressants: 1. to combine mechanisms of action not just drugs, 2. to combine antidepressants and to promote pharmacological synergy and tolerability, 3. to use important synergies within the serotonin, noradrenaline and even dopamine monoaminergic systems. Adequate treatment of depression including modern treatment approaches has the potential to reduce suffering and disability substantially and minimise the risk of suicide.