Arthritis and rheumatism
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Arthritis and rheumatism · Nov 2009
Randomized Controlled TrialTai Chi is effective in treating knee osteoarthritis: a randomized controlled trial.
To evaluate the effectiveness of Tai Chi in the treatment of knee osteoarthritis (OA) symptoms. ⋯ Tai Chi reduces pain and improves physical function, self-efficacy, depression, and health-related quality of life for knee OA.
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Arthritis and rheumatism · Nov 2009
Randomized Controlled TrialFunctional and work outcomes improve in patients with rheumatoid arthritis who receive targeted, comprehensive occupational therapy.
Work disability is a serious consequence of rheumatoid arthritis (RA). We conducted a 6-month, prospective randomized controlled trial comparing assessments of function, work, coping, and disease activity in employed patients with RA receiving occupational therapy intervention versus usual care. ⋯ Targeted, comprehensive occupational therapy intervention improves functional and work-related outcomes in employed RA patients at risk of work disability.
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Arthritis and rheumatism · Nov 2009
Randomized Controlled Trial Multicenter StudyEffects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: thirty-six-month results of a randomized, double-blind, controlled trial.
To compare the bone anabolic drug teriparatide (20 microg/day) with the antiresorptive drug alendronate (10 mg/day) for treating glucocorticoid-induced osteoporosis (OP). ⋯ Our findings indicate that subjects with glucocorticoid-induced OP treated with teriparatide for 36 months had greater increases in BMD and fewer new vertebral fractures than subjects treated with alendronate.
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Arthritis and rheumatism · Nov 2009
Review Multicenter StudyMacrophage activation syndrome in juvenile systemic lupus erythematosus: a multinational multicenter study of thirty-eight patients.
To describe the clinical and laboratory features of macrophage activation syndrome as a complication of juvenile systemic lupus erythematosus (SLE). ⋯ Our findings indicate that the occurrence of unexplained fever and cytopenia, when associated with hyperferritinemia, in a patient with juvenile SLE should raise the suspicion of macrophage activation syndrome. We propose preliminary guidelines for this syndrome in juvenile SLE to facilitate timely diagnosis and correct classification of patients.
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Arthritis and rheumatism · Nov 2009
Cancer risk in patients with rheumatoid arthritis treated with anti-tumor necrosis factor alpha therapies: does the risk change with the time since start of treatment?
To determine the short-term and medium-term risks of cancer in patients receiving anti-tumor necrosis factor alpha (anti-TNFalpha) therapies that have proven effective in the treatment of chronic inflammatory conditions. ⋯ During the first 6 years after the start of anti-TNF therapy in routine care, no overall elevation of cancer risk and no increase with followup time were observed.