Australian dental journal
-
Australian dental journal · Sep 2015
Randomized Controlled Trial Comparative StudyEffects of curcumin on crevicular levels of IL-1β and CCL28 in experimental gingivitis.
Curcumin has anti-inflammatory properties. The aim of this study was to compare interleukin-1β (IL-1β) and chemokine (C-C motif) ligand 28 (CCL28) levels following a topical application of curcumin (CRM), chlorhexidine (CHX) and chlorhexidine-metronidazole (CHX-MTZ) in an experimental gingivitis human model. ⋯ The anti-inflammatory potential of topical curcumin was similar to CHX-MTZ but superior to CHX in affecting IL-1β and CCL28 levels.