Current opinion in hematology
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Curr. Opin. Hematol. · Nov 2009
ReviewHemostatic strategies for minimizing mortality in surgery with major blood loss.
Continued hemorrhage remains a major contributor of mortality in massively transfused patients and controversy regarding their optimal management exists. This article reviews recent advances that impact the use and effectiveness of massive transfusion. ⋯ Implementation of more aggressive hemostatic resuscitation strategies in massively bleeding patients seems reasonable, and optimally, thrombelastography should be used to monitor coagulopathy and guide FFP and platelet transfusions.