Journal of the American College of Surgeons
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Pragmatic Clinical Trial
Multimodal Analgesic Strategies for Trauma: A Pragmatic Randomized Clinical Trial.
An effective strategy to manage acute pain and minimize opioid exposure is needed for injured patients. In this trial, we aimed to compare 2 multimodal pain regimens (MMPRs) for minimizing opioid exposure and relieving acute pain in a busy, urban trauma center. ⋯ The MAST MMPR was a generalizable and widely available approach that reduced opioid exposure after trauma and achieved adequate acute pain control.