Journal of the American College of Surgeons
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Comparative Study
Pathologic response to induction chemotherapy in locally advanced carcinoma of the breast: a determinant of outcome.
The prognosis for patients with locally advanced carcinoma of the breast remains poor. This study examines the pathologic evidence of response of the mammary tumor and axillary nodes after preoperative chemotherapy. We sought to determine if there was a relationship between the histologic response and clinical outcome. ⋯ These results indicate that patients whose tumors have the best pathologic response to induction chemotherapy experience the best outcome.
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Continuous arteriovenous hemofiltration does not improve survival in a canine model of septic shock.
We examined whether or not continuous arteriovenous hemofiltration (CAVH), in the absence of renal failure, would improve either hemodynamic abnormalities or survival in a canine model of septic shock. ⋯ The results of this study suggest that CAVH would be unlikely to provide benefit to patients with gram-negative septic shock, in the absence of renal failure.
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Case Reports
Techniques in the composite reconstruction of extensive thoracoabdominal tumor resections.
This report illustrates the unique problems of reconstructing thoracoabdominal wall defects coexisting with diaphragmatic defects. ⋯ Our report confirms the principle that, with modern thoracic and plastic operative techniques, the extent of tumor resection should not be compromised because of concern over the ability to reconstruct the defect.