Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
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An anisocoria produces a small relative afferent pupillary defect in the eye with the smaller pupil.
To determine whether an anisocoria can produce a relative afferent pupillary defect of clinical importance. ⋯ Clinically, approximately 0.1 log unit of relative afferent pupillary defect is produced in the eye with the smaller pupil for every millimeter of anisocoria. Therefore, the anisocoria must be larger than 2 mm in diameter difference to induce a clinically significant relative afferent pupillary defect.