Canadian respiratory journal : journal of the Canadian Thoracic Society
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Randomized Controlled Trial Multicenter Study
Impact of Candida species on clinical outcomes in patients with suspected ventilator-associated pneumonia.
The significance of Candida species in respiratory tract (RT) secretions in critically ill patients is unclear. ⋯ Patients with suspected VAP, in whom no bacterial pathogen was identified and in whom Candida species were isolated from RT cultures, exhibited a greater burden of illness compared with similar patients without Candida. Whether Candida species colonization of RT secretions is a marker of disease severity or actually contributes to poorer clinical outcomes remains unclear.