Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
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Charles Bonnet syndrome (CBS) is a widely under-recognised disorder typically characterised by complex visual hallucinations in the visually impaired. The lack of consensus over a uniform definition for CBS has much to do with the unresolved pathophysiology of the disorder. ⋯ While treatment aimed at improving the visual deficit can limit the symptoms of CBS, at present there is no reliably effective pharmacotherapy for the disorder. Once correctly recognised, a key management principle is to reassure the patient that CBS is a well-documented clinical entity that is not a harbinger of psychiatric illness.
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We report a patient with paradoxical brain embolism due to patent foramen ovale (PFO) associated with pulmonary embolism (PE). The number of microembolic signals, as detected by contrast saline transcranial Doppler (c-TCD) exam, drastically decreased with improvement of increased right atrial pressure due to PE. In a patient with paradoxical brain embolism associated with PE, c-TCD may be useful for both diagnosis of the presence of right-to-left shunting and evaluation of cardio-pulmonary circulation.