Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
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Multicenter Study Clinical Trial
Reducing post-lumbar puncture headaches with small bore atraumatic needles.
Lumbar puncture for testing of Alzheimer's disease pathophysiology for diagnostic confirmation is likely to become more common in the coming years. Minimizing adverse effects from this testing will be essential for clinical practice. ⋯ We assessed PLPH in the Alzheimer's Disease Neuroimaging Initiative cohort and found that PLPH occurrence was reduced only when using a 24 gauge atraumatic needle. We recommend that lumbar punctures for clinical and research purposes in Alzheimer's disease be conducted with 24 gauge atraumatic needles.