Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
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Neurocysticercosis (NCC) is an infection of the brain and its coverings by the larval stage of the tapeworm Taenia solium. It is the most common helminthic infestation of the central nervous system and a leading cause of acquired epilepsy worldwide. NCC induces neurological syndromes that vary from an asymptomatic infection to sudden death. ⋯ The selection of cases for medical or surgical treatments has improved and these two forms of therapy are complementary. In general, indications of surgery are: cysts that compress the brain and cranial nerves locally, intracranial hypertension or edema refractory to medical treatment, intraventricular NCC, spinal NCC with cord or root compression and ocular cysts. Recently, endoscopic approaches for ventricular NCC have been developed, which are now the treatment of choice for ventricular NCC with hydrocephalus.
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We aimed to evaluate the clinical utility and safety of the hook and rod method for occipitocervical fusion. Eleven consecutive patients (3 males, 8 females; 50-78 years old, average 63.8 years; 16-77 months follow-up, average 33.7 months) with unstable lesions at the craniocervical junction who underwent occipitocervical fusion using a hook and rod system were examined. A Compact Cotrel-Dubousset cervical system (Sofamor-Danek, Memphis TN, USA) was used in all patients. ⋯ No complications occurred during surgery. Solid bony fusion was obtained in all patients and no patient became clinically worse postoperatively. Occipitocervical fusion using a hook and rod system is a useful procedure that allows decompression of the spinal cord and secure spinal fusion at multiple levels simultaneously.
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Review
Hearing preservation after stereotactic radiosurgery for vestibular schwannoma: a systematic review.
Radiosurgery has evolved into an effective alternative to microsurgical resection in the treatment of patients with vestibular schwannoma. We performed a systematic analysis of the literature in English on the radiosurgical treatment of vestibular schwannoma patients. A total of 254 published studies reported assessable and quantifiable outcome data of patients undergoing radiosurgery for vestibular schwannomas. ⋯ Age of the patient was not a significant prognostic factor for hearing preservation rates (<65 years=58% vs. >65 years=62%; p=0.4317). The average overall follow-up was 41.2 months. Our data suggest that an overall hearing preservation rate of about 57% can be expected after radiosurgical treatment, and patients treated with 12.5 Gy were more likely to have preserved hearing.
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Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for patients with medically refractory Parkinson's disease (PD). The degree to which the anatomic location of the DBS electrode tip determines the improvement of contralateral limb movement function has not been defined. This retrospective study was performed to address this issue. ⋯ Two-tailed t-tests revealed no significant difference in electrode tip location between the two groups in three-dimensional distance (p=0.759), lateral-medial (x) axis (p=0.983), anterior-posterior (y) axis (p=0.949) or superior-inferior (z) axis (p=0.894) from the intended anatomical target. The range of difference in tip location and limb scores was extensive. Our results suggest that anatomic targeting alone may provide the same clinical efficacy as is achieved by "fine-tuning" DBS placement with microelectrode recording to a specific target.
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Case Reports
Immediate postoperative death due to hypothalamic injury following surgery for craniopharyngioma.
Autonomic disturbances due to hypothalamic injury that result in postoperative death are rare complications following surgery for craniopharyngioma. We discuss the case of a child who died due to hypothalamic injury following radical excision of a multi-compartmental craniopharyngioma. Mechanisms and clinical manifestations of hypothalamic injury and ways to avoid this fatal complication are discussed.