Menopause : the journal of the North American Menopause Society
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Randomized Controlled Trial Comparative Study
Short- and long-term effects of continuous versus intermittent restrictive diet approaches on body composition and the metabolic profile in overweight and obese postmenopausal women: a pilot study.
The objective of this study was to compare changes in body composition and the metabolic profile between women taking an intermittent diet (ID) and women taking a continuous diet (CD). ⋯ The ID resulted in similar short- and long-term changes in body composition and metabolic profile compared with a CD. Most improvements occurred during the first 5 weeks of treatment in both interventions.
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Formononetin (Formo) prevents ovariectomy (Ovx)-induced bone loss in rats. However, there are no reports on the curative effects of Formo. The objective of this study was to investigate the ability of Formo in restoring trabecular microarchitecture and promoting new bone formation in osteopenic rats. ⋯ Daily oral administration of Formo for 12 weeks has a substantial anabolic effect, thus raising the possibility of its use in postmenopausal osteoporosis.