Journal of travel medicine
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Insecticide treatments in aircraft (termed 'aircraft disinsection') aim to support the containment of potentially disease-carrying vector insects. The introduction of non-endemic mosquito species is of concern as some mosquitoes can act as vectors of many serious human diseases. Expansion of vectors to previously non-endemic regions, extended flight networks and mosquito resistance to insecticides pose challenges to contemporary vector-control approaches. Despite established efficacy of aircraft disinsection in trials, there is increasing concern over its effectiveness and feasibility in flight operations, and its usefulness as a public health measure. ⋯ Concerns about the introduction of non-endemic mosquito vectors reinforce the need for effective preventive measures. Import of disease vectors is likely to occur in the future under changing environmental and operational conditions. Optimal impact from disinsection requires appropriate deployment, commitment and use. The current system of evaluation is inadequate for producing the evidence needed for informed policy decisions. While utilizing the results of research into environmentally sustainable vector-control methods for use in aircraft, future approaches to aircraft disinsection require improved evidence of anticipated benefits and harms, reliable monitoring data on insecticide resistance, and must be supported by strong vector control at airports.
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In many countries, patients with mild coronavirus disease 2019 (COVID-19) are told to self-isolate at home, but imperfect compliance and shared living space with uninfected people limit the effectiveness of home-based isolation. We examine the impact of facility-based isolation compared to self-isolation at home on the continuing epidemic in the USA. ⋯ Timely facility-based isolation for mild COVID-19 cases could substantially reduce the number of new infections and effectively curb the continuing epidemic in the USA. Local epidemic burdens should determine the scale of facility-based isolation strategies.
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Letter Case Reports
Pitfalls of exceptions for COVID-19 travel quarantine: lessons from a dignitary visit to Thailand.
A dignitary from a European country made an official visit to Thailand in November 2020. Due to the nature of this visit, a standard 14-day quarantine was not implemented. After a series of meetings with diplomats and hotel staffers, the dignitary was diagnosed with COVID-19. Here, we detailed the transmission and the genomic investigation from the visit, presenting the factors that need to be considered when a standard quarantine was waivered.
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The emerging N501Y mutation in severe acute respiratory syndrome coronavirus 2, which becomes prevalent in the UK rapidly, is one of the major challenges of COVID-19 control. To explore the transmission advantage, we estimate that the N501Y substitution increases the infectivity by 52% (95% confidence interval: 46, 58) in terms of the reproduction number.