QJM : monthly journal of the Association of Physicians
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Comparative Study
A comparison of lorazepam and diazepam as initial therapy in convulsive status epilepticus.
Previous trials have suggested lorazepam may be superior to diazepam as first-line treatment of convulsive status epilepticus (CSE), with improved seizure outcome, and a lower incidence of side-effects. Many published guidelines however still recommend diazepam. ⋯ We recommend that lorazepam be the first-line therapy in preference to diazepam in adults with CSE.