JNMA; journal of the Nepal Medical Association
-
JNMA J Nepal Med Assoc · Nov 2022
Multiple Pregnancy among Deliveries in a Tertiary Care Center: A Descriptive Cross-sectional Study.
Multiple pregnancy is associated with increased obstetric complications as well as poor perinatal outcomes in developing countries because of the increased risk to both mother and baby. So better understanding of the risk factors is required to improve the quality of perinatal care. The aim of the study was to find out the prevalence of multiple pregnancies among deliveries in a tertiary care centre. ⋯ low birth weight; multiple pregnancy; preterm.
-
Dysgerminoma is the most common malignant germ cell tumour of the ovary. Abdominal pain, abdominal distention, and the presence of a palpable mass are common symptoms at presentation. This is usually detected in youth, before the age of 20 years. Ovarian or adnexal tumours are very rare in patients below the age of 18 years, most of them being functional cysts, only 10% being malignant. Here is a rare case of an 8 years old girl with dysgerminoma who underwent right-sided salpingo-oophorectomy for unilateral involvement with conservation of fertility and now the patient is on chemotherapy as the tumour metastasized to the pre-aortic lymph node. ⋯ case reports; dysgerminoma; metastasis; paediatrics.
-
JNMA J Nepal Med Assoc · Nov 2022
Case ReportsAnti-N-methyl-D-aspartate Receptor Autoimmune Encephalitis: A Case Report.
Anti-N-methyl-D-aspartate receptor encephalitis is a form of autoimmune encephalitis with acute or subacute neuropsychiatric symptoms. Despite this fact, due to a couple of factors, this condition remains insufficiently acknowledged and is an under-recognised clinical scenario. We describe a case of a patient presenting with fever, headache and altered sensorium along with a history of disorientation, episodes of abnormal body movements and loss of consciousness in the later phase. She was initially thought to have Status epilepticus with tuberculous meningoencephalitis but her cognitive functions did not improve despite appropriate treatment. She displayed features away from the usual course of disease leading to suspicions of Autoimmune Encephalitis and Anti-N-methyl- D-aspartate receptor reports later confirmed the diagnosis. Methylprednisolone and Intravenous Immunoglobulin was started empirically and she was discharged in stable health with stabilised emotional and cognitive function with Azathioprine and Levetiracetam continued. Our findings suggested early diagnosis and prompt immunotherapy treatment beneficial for the outcome. ⋯ ase reports; encephalitis; immunotherapy; methylprednisolone.
-
JNMA J Nepal Med Assoc · Nov 2022
Abruptio Placenta among Pregnant Women Admitted to the Department of Obstetrics and Gynaecology in a Tertiary Care Centre: A Descriptive Cross-sectional Study.
Abruptio placenta is the complete or partial separation of the normally implanted placenta before delivery of the foetus. It is one of the commonest causes of antepartum haemorrhage affecting maternal and foetal outcomes. Early detection and timely intervention of abruptio placenta in daily clinical practice are important to improve maternal and perinatal outcomes. The objective of the study was to find out the prevalence of abruptio placenta among the pregnant women admitted to the Department of Obstetrics and Gynaecology in a tertiary care centre. ⋯ abruptio placenta; epidemiology; fetal outcome; incidence; maternal outcome.
-
JNMA J Nepal Med Assoc · Nov 2022
Case ReportsUrine Discoloration Associated with Metronidazole: A Case Report.
Metronidazole belongs to the nitroimidazole group of antibiotics. It is used for the treatment of anaerobic and protozoal organisms. Its common side effects are nausea, vomiting, headache, and abdominal pain. Urine discolouration is one of the rare side effects of metronidazole. We report a case of 4-years-old male, a known case of Steroid resistant nephrotic syndrome; Focal Segmental Glomerulosclerosis type who developed reddish discolouration of urine following the introduction of oral metronidazole which reverted back to its usual colour within 24 hours of discontinuing metronidazole. With no evidence of other possible causes, urine discolouration was linked with the use of metronidazole. Urine discoloration as a side effect of metronidazole is rarely reported in the literature. This case report of the rare adverse effects of the commonly used drug can be of importance in the scientific community. Urine discolouration could be considered a side effect of metronidazole when there is no other obvious cause. ⋯ flagyl; hematuria; metronidazole; side effects of drugs.