JNMA; journal of the Nepal Medical Association
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JNMA J Nepal Med Assoc · Apr 2023
Retinopathy of Prematurity among Preterm Newborn Admitted to the Neonatal Care Unit in a Tertiary Care Centre: A Descriptive Cross-sectional Study.
World Health Organization has identified retinopathy of prematurity as an important cause of preventable childhood blindness. The presentation of retinopathy of prematurity is varied and differs in the developed and developing worlds. The study aimed to find out the prevalence of retinopathy of prematurity among preterm newborn admitted to the Neonatal Care Unit in a tertiary care centre. ⋯ blood transfusion; low birth weight; oxygen; preterm births; retinopathy of prematurity.
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JNMA J Nepal Med Assoc · Apr 2023
Case ReportsTerbinafine-induced Toxic Epidermal Necrolysis in Pregnancy: A Case Report.
Toxic epidermal necrolysis in pregnancy is a rare disease that can have an adverse effect on Toxic epidermal necrolysis in pregnancy is a rare disease that can have an adverse effect on pregnancy outcomes. Common etiology of the condition includes medication triggered followed by mycoplasma infection. Almost one-third of cases are idiopathic. Despite the rarity of data, terbinafine causing toxic epidermal necrolysis has been reported. Toxic epidermal necrolysis manifests as a macule, erythema followed by a blister in the chest and spreading to other parts of the body. Removal of the offending agent and supportive management is the cornerstone of management. Here we report 22-year-old primipara pregnant women presenting with toxic epidermal necrolysis after 3 weeks of oral terbinafine use with good pregnancy outcomes. ⋯ case reports; pregnancy; Stevens-Johnson syndrome; toxic epidermal necrolysis.
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Reported here is a rare near-miss case of stroke in pregnancy presented to the Department of Obstetrics and Gynaecology. A 38 years gravida 8 was referred from a private hospital on 18 November 2022 with hemorrhagic stroke, a known case of chronic hypertension at 37 weeks of gestation with previous cesarean section and acute kidney injury. At a private hospital computed tomography head was done it showed intracerebral haemorrhage. On cesarean, intraoperatively it was a live female with thick meconium. The patient was kept in intensive care with a mechanical ventilator, antihypertensives, antibiotics, and analgesics. Serum creatinine was increasing daily. Suture was cut on the 7th postoperative and two times dialysis was done on the 8th and 9th postoperative days. Stroke in pregnancy is a rare diagnosis and it could have been prevented by regular antenatal visits and early referral antenatally along with a multidisciplinary approach. ⋯ case reports; hypertension; intracerebral haemorrhage; pregnancy; stroke.
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JNMA J Nepal Med Assoc · Apr 2023
Hypothyroidism among Type 2 Diabetic Patients Visiting Outpatient Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study.
Diabetes-thyroid relationship is said to be bidirectional. Insulin resistance and hyperinsulinemia in type 2 diabetes mellitus increase free thyroxine but decrease free tri-iodothyronine and thyroid-releasing hormone synthesis. Thyroid dysfunction may in turn impose an adverse effect on glucose metabolism in type 2 diabetes mellitus. Undetected thyroid dysfunction can worsen glycemic control and predispose type 2 diabetes mellitus patients to cardiovascular and other diabetes-related complications. Recognition and timely treatment of thyroid dysfunction in type 2 diabetes mellitus patients can delay diabetic complications. The aim of this study was to find out the prevalence of hypothyroidism among type 2 diabetic patients visiting the outpatient Department of Internal Medicine of a tertiary care centre. ⋯ chronic kidney disease; thyroid stimulating hormone; thyroxine; triiodothyronine.
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JNMA J Nepal Med Assoc · Apr 2023
Preterm Neonates Admitted in the Neonatal Intensive Care Unit at a Tertiary Care Centre: A Descriptive Cross-sectional Study.
Preterm birth, one of the leading causes of admissions to the Neonatal intensive care unit, is a major contributor to neonatal morbidity and mortality in developing countries. This study aimed to find out the prevalence of premature neonates admitted to the Neonatal Intensive Care Unit of a tertiary care centre. ⋯ morbidity; neonatal; neonatal intensive care unit; premature birth.