Journal of cardiac failure
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Randomized Controlled Trial Multicenter Study Clinical Trial
Effects of metoprolol CR/XL on mortality and hospitalizations in patients with heart failure and history of hypertension.
We describe the effect of controlled-release/extended-release (CR/XL) metoprolol succinate once daily on mortality and hospitalizations among patients with a history of hypertension complicated by chronic systolic heart failure. ⋯ A subgroup analysis of MERIT-HF shows that patients with heart failure and a history of hypertension received a similar benefit from metoprolol CR/XL treatment as all patients included in the total study.