Journal of cardiac failure
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Pulmonary hypertension occurs in 60% to 80% of patients with heart failure and is associated with high morbidity and mortality. ⋯ Many drugs used for idiopathic pulmonary arterial hypertension are being considered as treatment options for heart failure-related pulmonary hypertension. This is of particular significance in the heart transplant population. Randomized clinical trials with interventions targeting heart failure patients with elevated pulmonary artery pressure would be justified.