Haemophilia : the official journal of the World Federation of Hemophilia

The most recent articles from: Haemophilia January 2016

Haemophilia · Jan 2016

Perioperative management and outcome of fracture treatment in patients with haemophilia without inhibitors.

Fractures in persons with haemophilia (PWH) are not uncommon and require an interdisciplinary approach to maintain haemostasis during surgical treatment. ⋯ An optimal interdisciplinary perioperative management provided the surgical treatment of fractures in PWH can be performed safely with a low complication rate.

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Haemophilia · Jan 2016

Observational Study

First prospective report on immune tolerance in poor risk haemophilia A inhibitor patients with a single factor VIII/von Willebrand factor concentrate in an observational immune tolerance induction study.

Development of neutralizing inhibitors against factor VIII (FVIII) is a major complication of haemophilia A treatment. ⋯ Treatment with a single pdFVIII/VWF concentrate, mainly according to the Bonn protocol, resulted in a high ITI success rate in haemophilia A patients with inhibitors and poor prognosis for ITI success.

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