Journal of investigative medicine : the official publication of the American Federation for Clinical Research
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African Americans commonly have normal high-density lipoprotein cholesterol (HDL-C) and low triglyceride levels despite having insulin resistance and obesity. The higher than expected HDL-C levels are usually attributed to low levels of hepatic triglyceride lipase (HTGL) activity. Factors that regulate HTGL in African Americans are not well delineated. ⋯ The data suggest that adiponectin is a significant metabolic concomitant of HTGL activity in African Americans.