Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2005
Randomized Controlled Trial Multicenter Study Clinical TrialRandomised controlled trial evaluating effects of morphine on plasma adrenaline/noradrenaline concentrations in newborns.
To determine the effects of continuous morphine infusion in ventilated newborns on plasma concentrations of adrenaline (epinephrine) and noradrenaline (norepinephrine) and their relation to clinical outcome. ⋯ Continuous morphine infusion significantly decreased plasma noradrenaline concentrations in ventilated newborns compared with placebo treatment. The results of this study support the idea that routine morphine administration decreases stress responses in ventilated neonates.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2005
Multicenter StudyBenefit of antenatal glucocorticoids according to the cause of very premature birth.
In this observational study performed in a large cohort of very preterm singletons, respiratory outcome was found to be strongly dependent on the cause of premature delivery. Although less apparent in infants born to mothers with chorioamnionitis, exposure to antenatal glucocorticoids remained significantly associated with a decrease in the incidence of respiratory distress syndrome after adjustment for the main cause of premature birth.