Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Jul 2008
ReviewNeurocognitive outcome following fetal growth restriction.
This review evaluates neurological and cognitive outcomes as they relate to fetal growth restriction. The aim is to clarify the relationship between poor fetal growth and abnormal brain development in order to understand the research directions required to untangle this complex issue.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jul 2008
N-terminal pro-B-type natriuretic peptide: a measure of significant patent ductus arteriosus.
B-type natriuretic peptide (BNP) is a marker for ventricular dysfunction secreted as a pre-prohormone, pro-B-type natriuretic peptide (proBNP), and cleaved into BNP and a biologically inactive fragment, N-terminal pro-B-type natriuretic peptide (NT-proBNP). Little is known about the clinical usefulness of NT-proBNP in preterm infants. ⋯ Plasma NT-proBNP level on day 3 is a good marker for hsPDA in preterm infants. Serial measurements of NT-proBNP may be useful in assessing the clinical course of PDA.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jul 2008
Randomized Controlled TrialPharyngeal pressure value using two continuous positive airway pressure devices.
The aim of the study was to measure the difference between the set continuous positive airway pressure (CPAP) value and the pharyngeal pressure reading during CPAP in premature infants with mild respiratory distress syndrome, using two different devices: hood CPAP and the conventional nasal system. The preliminary results suggest that hood CPAP may produce more stable pharyngeal pressure than the conventional nasal device.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jul 2008
A trial of spontaneous breathing to determine the readiness for extubation in very low birth weight infants: a prospective evaluation.
Extubation failure in premature infants is common. A spontaneous breathing trial (SBT) was prospectively evaluated to determine timing of extubation. Compared with historical controls, infants were extubated at significantly higher ventilator rates and airway pressures using the SBT. No differences in rates of bronchopulmonary dysplasia or duration of ventilation were seen.