Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2010
ReviewMannose-binding lectin and infection risk in newborns: a systematic review.
The authors systematically reviewed the literature on mannose-binding lectin (MBL) and infections in newborns to determine whether infection risk is increased in MBL-deficient newborns. All original reports on MBL and infections in newborns were retrieved from Embase, Medline and CENTRAL from 1966 to December 2009. Information extracted from each article included study design, definitions of MBL deficiency and neonatal infection, follow-up period and risk factor analysis. ⋯ Newborns with low MBL levels appear to have culture-confirmed sepsis more frequently than MBL-sufficient newborns. However, the influence of confounding factors was analysed insufficiently. Variant MBL2 genotypes appear to have less influence.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2010
Randomized Controlled TrialSweeten, soother and swaddle for retinopathy of prematurity screening: a randomised placebo controlled trial.
To assess the efficacy of oral sucrose combined with swaddling and non-nutritive suck (NNS) as a method for reducing pain associated with retinopathy of prematurity (ROP) screening. ⋯ ROP screening is a necessary but recognised painful procedure. Sucrose combined with NNS and swaddling reduced the behavioural and physiological pain responses. However, pain scores remained consistently high and appropriate pain relief for ROP screening remains a challenge.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2010
Assessment of tidal volume and gas leak during mask ventilation of preterm infants in the delivery room.
The aim was to compare resuscitators' estimates of tidal volume (V(T)) and face mask leak with measured values during positive pressure ventilation (PPV) of newborn infants in the delivery room. ⋯ During face mask ventilation in the delivery room, V(T) and face mask leak were large and variable. The resuscitators were unable to accurately assess their face mask leak or delivered V(T).
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2010
Passive cooling for initiation of therapeutic hypothermia in neonatal encephalopathy.
To determine the feasibility of passive cooling to initiate therapeutic hypothermia before and during transport. ⋯ Passive cooling is a simple and effective technique if portable cooling equipment is unavailable. Rectal temperature monitoring is essential; active cooling methods without core temperature monitoring may lead to overcooling.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2010
Leak and obstruction with mask ventilation during simulated neonatal resuscitation.
To evaluate mask technique during simulated neonatal resuscitation and test the effectiveness of training in optimal mask handling. ⋯ Mask ventilation during simulated neonatal resuscitation was often hampered by large leaks at the face mask. Moderate airway obstruction occurred frequently when effort was taken to minimise leak. Training in mask ventilation reduced mask leak but should also focus on preventing airway obstruction.