Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Mar 2010
Randomized Controlled TrialRemifentanil for endotracheal intubation in neonates: a randomised controlled trial.
To evaluate the efficacy and safety of remifentanil as a premedication in neonates undergoing elective endotracheal intubation. ⋯ Although remifentanil is comparable to fentanyl and succinylcholine in attenuating adverse physiologic responses during neonatal intubation, muscle rigidity is a concern at doses of 3 microg/kg. Further trials are required to evaluate ideal dosing regimens and combinations of agents for use with remifentanil in neonates.
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Arch. Dis. Child. Fetal Neonatal Ed. · Mar 2010
Randomized Controlled TrialNasal continuous positive airway pressure (CPAP) versus bi-level nasal CPAP in preterm babies with respiratory distress syndrome: a randomised control trial.
To evaluate the clinical course, respiratory outcomes and markers of inflammation in preterm infants with moderate respiratory distress syndrome (RDS) assigned from birth to nasal continuous positive airway pressure (NCPAP) or bi-level NCPAP. ⋯ Bi-level NCPAP was associated with better respiratory outcomes versus NCPAP, and allowed earlier discharge, inducing the same changes in the cytokine levels. It was found to be well tolerated and safe in the study population.
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Arch. Dis. Child. Fetal Neonatal Ed. · Mar 2010
Antenatal corticosteroids and neonatal outcomes according to gestational age: a cohort study.
To see whether there was any difference in the effect of antenatal corticosteroids on neonatal outcomes according to different gestational ages at birth. ⋯ Antenatal corticosteroid treatment is associated with improved survival in babies born between 24 and 29 weeks' gestation. This, however, does not lead to any significant improvements in length of stay, duration of respiratory support and CLD among survivors.