Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Jul 2010
Review Meta AnalysisOpioids for neonates receiving mechanical ventilation: a systematic review and meta-analysis.
To evaluate the effect of opioid analgesics, compared to placebo, no drug, or other non-opioid analgesics or sedatives, on pain, duration of mechanical ventilation, mortality, growth and neurodevelopmental outcomes in newborn infants on mechanical ventilation. ⋯ There is insufficient evidence to recommend routine use of opioids in mechanically ventilated newborns. Opioids should be used selectively, when indicated by clinical judgment and evaluation of pain indicators. If sedation is required, morphine is safer than midazolam.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jul 2010
Multicenter StudyValidation of a neonatal pain scale adapted to the new practices in caring for preterm newborns.
BACKGROUND Neonatal pain assessment generally requires access to facial expression. Improved neonatology practices, such as greater protection against bright lights and non-invasive mask ventilation, have made facial observation more difficult. ⋯ FANS, which is reliable and valid, is the first scale to score pain in preterm newborns when facial expression is not accessible.