Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2012
Randomized Controlled Trial Comparative StudyEfficacy of tramadol versus fentanyl for postoperative analgesia in neonates.
To assess, in newborn infants submitted to surgical procedures, the efficacy of two opioids-fentanyl and tramadol-regarding time to extubate, time to achieve 100 ml/kg of enteral feeding and pain in the first 72 h after surgery. ⋯ Tramadol was as effective as fentanyl for postoperative pain relief in neonates but does not appear to offer advantages over fentanyl regarding the duration of mechanical ventilation and time to reach full enteral feeding. Trial registration NCT00713726.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 2012
Outcomes following the surgical ligation of the patent ductus arteriosus in premature infants in Scotland.
To determine morbidity, mortality and associated risk factors following patent ductus arteriosus (PDA) ligation in premature infants. ⋯ PDA ligation is well tolerated, with evidence of early benefit. The incidence of neurodisability or death from BPD at 1 year remains high. Increasing preoperative FiO(2) and lack of prior treatment with COIs are associated with increased mortality at 1 year.