Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2012
Randomized Controlled Trial Comparative StudyRandomised weaning trial comparing assist control to pressure support ventilation.
To determine if the work of breathing was lower, respiratory muscle strength greater, but the degree of asynchrony higher during weaning by assist control ventilation (ACV) rather than pressure support ventilation (PSV) and if any differences were associated with a shorter duration of weaning. ⋯ No significant differences were found between weaning by PSV and ACV when similar inflation times were used.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2012
Randomized Controlled TrialBrain injury following trial of hypothermia for neonatal hypoxic-ischaemic encephalopathy.
The objective of our study was to examine the relationship between brain injury and outcome following neonatal hypoxic-ischaemic encephalopathy treated with hypothermia. ⋯ Fewer areas of infarction and a trend towards more normal scans were noted in brain MRI following whole-body hypothermia. Presence of the NICHD pattern of brain injury is a marker of death or moderate or severe disability at 18-22 months following hypothermia for neonatal encephalopathy.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2012
C reactive protein: impact on peripheral tissue oxygenation and perfusion in neonates.
C reactive protein (CRP) is a sensitive marker of acute inflammation of infectious and non-infectious origin. Aim was to use near-infrared spectroscopy (NIRS) to analyse peripheral oxygenation and perfusion in term and preterm neonates with elevated CRP levels, at a time when routine haemodynamic variables are still normal. ⋯ Inflammatory processes with CRP elevation cause impaired peripheral oxygenation and perfusion in neonates even when routine haemodynamic variables are still normal. NIRS might offer a new non-invasive tool for the early recognition and diagnosis of infectious and non-infectious inflammatory processes.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2012
Delayed cord clamping and blood flow in the superior vena cava in preterm infants: an observational study.
To determine if timing of cord clamping affects blood flow in the upper body, as measured by flow in the superior vena cava (SVC). ⋯ Blood flow in the SVC was higher in infants where delayed cord clamping was performed. The relationship of IVH, low flow and timing of cord clamping requires further study.