Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2015
Randomized Controlled TrialNon-invasive neurally adjusted ventilatory assist in preterm infants: a randomised phase II crossover trial.
To compare non-invasive ventilation neurally adjusted ventilatory assist (NIV-NAVA) and non-invasive pressure support (NIV-PS) in preterm infants on patient-ventilator synchrony. ⋯ NAVA improved patient-ventilator synchrony and diaphragmatic unloading in preterm infants during non-invasive nasal ventilation even in the presence of large air leaks.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2015
Clinical TrialChange in tidal volume during cardiopulmonary resuscitation in newborn piglets.
The purpose of inflations during cardiopulmonary resuscitation (CPR) is to deliver an adequate tidal volume (VT) to facilitate gas exchange. However, no study has examined VT delivery during chest compression (CC) in detail to understand the effect of CC on lung aeration. The aim of the study was to examine VT changes during CC and their effect on lung aeration. ⋯ VT delivery is improved using CC+SI compared with 3:1 C:V. This improvement in VT delivery may lead to better alveolar oxygen delivery and lung aeration.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2015
Effectivity of ventilation by measuring expired CO2 and RIP during stabilisation of preterm infants at birth.
To measure tidal volume, plethysmography changes and gas exchange during respiratory support at birth. ⋯ While Vte during breathing on CPAP was lower compared with PPV coinciding with breathing, breathing on CPAP was most effective in gas exchange and plethysmography amplitude gain compared with PPV and PPV coinciding with breathing.
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Arch. Dis. Child. Fetal Neonatal Ed. · Nov 2015
Observational StudyOutcomes of infants with Apgar score of zero at 10 min: the West Australian experience.
Infants who have an Apgar score of zero at 10 min of age are known to have poor long-term prognosis. Expert committee guidelines suggest that it is reasonable to cease resuscitation efforts if the asphyxiated infant does not demonstrate a heart beat by 10 min of life. These guidelines are based on data from the era when therapeutic hypothermia was not the standard of care for hypoxic ischaemic encephalopathy (HIE). Hence, we aimed to review our unit data from the era of therapeutic hypothermia to evaluate the outcomes of infants who had an Apgar score of zero at 10 min and had survived to reach the neonatal intensive care unit. ⋯ 4 out of 13 (30.7%) infants with 10 min Apgar scores of zero who survived to reach the neonatal intensive care unit had normal scores on formal developmental assessments. Information from large databases (preferably population based) is necessary to review recommendations regarding stopping delivery room resuscitation in term infants.