Archives of disease in childhood. Fetal and neonatal edition
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 1997
Randomized Controlled Trial Comparative Study Clinical TrialRandomised controlled trial of colloid or crystalloid in hypotensive preterm infants.
To compare the efficacy of a colloid (5% albumin) and a crystalloid (isotonic saline) solution for treating hypotension in mechanically ventilated preterm infants. ⋯ Isotonic saline is as effective as 5% albumin for treating hypotension in preterm infants, and it has the additional advantage of causing less fluid retention in the first 48 hours.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 1997
Use of neonatal intensive care unit as a safe place for neonatal surgery.
To evaluate the advantages, disadvantages, and short term morbidity and mortality of major surgical interventions performed in the neonatal intensive care unit. ⋯ The neonatal intensive care unit is suitable for major surgery during the neonatal period and no special area is needed to perform complication free surgery.
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Arch. Dis. Child. Fetal Neonatal Ed. · Jan 1997
Association between blood lactate and acid-base status and mortality in ventilated babies.
To investigate the relation between common acid-base parameters and blood lactate concentrations and their prognostic importance in sick, ventilated neonates. ⋯ Contrary to popular belief, pH or base excess cannot be used as proxy measures for blood lactate concentration, and independent measurement of the latter are needed. Blood lactate concentrations may provide an early warning signal and important prognostic information in ill, ventilated neonates. In this regard, serial measurements of blood lactate are more useful than a single value.
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Arch. Dis. Child. Fetal Neonatal Ed. · Sep 1996
Randomized Controlled Trial Clinical TrialAlfentanil as procedural pain relief in newborn infants.
To assess the need for, and the suitability of, alfentanil for pain relief during tracheal suction used in assisted ventilation in newborn infants. ⋯ Tracheal suction is a painful procedure. The dose of alfentanil required for pain relief (20 micrograms/kg) causes a high incidence of rigidity and thus should be used only with muscle relaxant.
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Arch. Dis. Child. Fetal Neonatal Ed. · Sep 1996
Comparative Study Clinical Trial Controlled Clinical TrialComparison of effects of 95% and 90% oxygen saturations in respiratory distress syndrome.
To determine if decreasing arterial blood saturation from 95% to 90% could cause vasoconstriction of the pulmonary vasculature and dilatation of a patent ductus arteriosus in preterm newborn infants with respiratory distress syndrome (RDS). ⋯ A decrease from 95% to 90% SpO2 did not have any effect on the pulmonary circulatory haemodynamics nor the ductus arteriosus.