The journals of gerontology. Series A, Biological sciences and medical sciences
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J. Gerontol. A Biol. Sci. Med. Sci. · Oct 2017
Association of Accelerometer-Measured Physical Activity With Leukocyte Telomere Length Among Older Women.
Previous studies on physical activity and telomere length have relied largely upon self-reported physical activity data, and few studies have examined older adults. The association of objectively measured physical activity with leukocyte telomere length (LTL) is currently unknown. ⋯ Older women meeting current recommendations of ≥2.5 h/wk of MVPA, as assessed by accelerometer, had longer LTL. Additional studies using accelerometers in large, diverse cohorts of older women are needed to confirm and extend these findings.
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J. Gerontol. A Biol. Sci. Med. Sci. · Oct 2017
Randomized Controlled Trial Multicenter StudyBaseline Characteristics of Participants in the ASPREE (ASPirin in Reducing Events in the Elderly) Study.
There are no primary prevention trials of aspirin with relevant geriatric outcomes in elderly people. ASPirin in Reducing Events in the Elderly (ASPREE) is a placebo-controlled trial of low-dose aspirin that will determine whether 5 years of daily 100-mg enteric-coated aspirin extends disability-free and dementia-free life in a healthy elderly population and whether these benefits outweigh the risks. ⋯ Findings from ASPREE will be generalizable to a healthier older population in both countries and will assess whether the broad benefits of daily low-dose aspirin in prolonging independent life outweigh the risks.
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J. Gerontol. A Biol. Sci. Med. Sci. · Oct 2017
Stabilized Incidence in Proximal Humeral Fractures of Elderly Women: Nationwide Statistics From Finland in 1970-2015.
Low-trauma fractures of elderly women are a major public health concern. ⋯ The clear rise in the incidence of low-trauma proximal humeral fractures in Finnish elderly women from early 1970s until mid 1990s has been followed by stabilized fracture rates. Reasons for this are largely unknown, but a cohort effect toward a healthier aging population with improved functional ability, as well as measures to prevent falls and alleviate fall severity, could partly explain the phenomenon.