American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
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The uses, dosing recommendations, benefits, and disadvantages of unlabeled drugs administered by nebulization are reviewed. ⋯ Unlabeled nebulization of opioids, lidocaine, magnesium, amphotericin B, and colistin is an alternative method of treatment for patients with pulmonary problems or infections or for those undergoing bronchoscopy. More research is needed to develop guidelines for their use since nebulization may provide benefits to many patients who otherwise cannot be treated or would be at risk of systemic adverse effects of the drugs.